Phenillin
Phenillin Brand names, Phenillin Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Phenillin Brand Names Mixture
- No information avaliable
Phenillin Chemical_Formula
C15H10O2
Phenillin RX_link
No information avaliable
Phenillin fda sheet
Phenillin msds (material safety sheet)
Phenillin Synthesis Reference
No information avaliable
Phenillin Molecular Weight
222.239 g/mol
Phenillin Melting Point
148-151 oC
Phenillin H2O Solubility
27 mg/L (at 20 oC)
Phenillin State
Solid
Phenillin LogP
2.917
Phenillin Dosage Forms
Tablet
Phenillin Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Phenillin Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Phenillin Absorption
Absorbed slowly from the gastrointestinal tract.
Phenillin side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Phenillin Patient Information
No information avaliable
Phenillin Organisms Affected
Humans and other mammals
