Hedulin en es it fr

Hedulin Brand names, Hedulin Analogs

Hedulin Brand Names Mixture

  • No information avaliable

Hedulin Chemical_Formula


Hedulin RX_link

No information avaliable

Hedulin fda sheet

Hedulin msds (material safety sheet)

Hedulin MSDS

Hedulin Synthesis Reference

No information avaliable

Hedulin Molecular Weight

222.239 g/mol

Hedulin Melting Point

148-151 oC

Hedulin H2O Solubility

27 mg/L (at 20 oC)

Hedulin State


Hedulin LogP


Hedulin Dosage Forms


Hedulin Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Hedulin Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Hedulin Absorption

Absorbed slowly from the gastrointestinal tract.

Hedulin side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Hedulin Patient Information

No information avaliable

Hedulin Organisms Affected

Humans and other mammals