Hedulin
Hedulin Brand names, Hedulin Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Hedulin Brand Names Mixture
- No information avaliable
Hedulin Chemical_Formula
C15H10O2
Hedulin RX_link
No information avaliable
Hedulin fda sheet
Hedulin msds (material safety sheet)
Hedulin Synthesis Reference
No information avaliable
Hedulin Molecular Weight
222.239 g/mol
Hedulin Melting Point
148-151 oC
Hedulin H2O Solubility
27 mg/L (at 20 oC)
Hedulin State
Solid
Hedulin LogP
2.917
Hedulin Dosage Forms
Tablet
Hedulin Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Hedulin Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Hedulin Absorption
Absorbed slowly from the gastrointestinal tract.
Hedulin side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Hedulin Patient Information
No information avaliable
Hedulin Organisms Affected
Humans and other mammals
