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Fenindion Brand names, Fenindion Analogs

Fenindion Brand Names Mixture

  • No information avaliable

Fenindion Chemical_Formula


Fenindion RX_link

No information avaliable

Fenindion fda sheet

Fenindion msds (material safety sheet)

Fenindion MSDS

Fenindion Synthesis Reference

No information avaliable

Fenindion Molecular Weight

222.239 g/mol

Fenindion Melting Point

148-151 oC

Fenindion H2O Solubility

27 mg/L (at 20 oC)

Fenindion State


Fenindion LogP


Fenindion Dosage Forms


Fenindion Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Fenindion Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Fenindion Absorption

Absorbed slowly from the gastrointestinal tract.

Fenindion side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Fenindion Patient Information

No information avaliable

Fenindion Organisms Affected

Humans and other mammals