Theradione
Theradione Brand names, Theradione Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Theradione Brand Names Mixture
- No information avaliable
Theradione Chemical_Formula
C15H10O2
Theradione RX_link
No information avaliable
Theradione fda sheet
Theradione msds (material safety sheet)
Theradione Synthesis Reference
No information avaliable
Theradione Molecular Weight
222.239 g/mol
Theradione Melting Point
148-151 oC
Theradione H2O Solubility
27 mg/L (at 20 oC)
Theradione State
Solid
Theradione LogP
2.917
Theradione Dosage Forms
Tablet
Theradione Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Theradione Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Theradione Absorption
Absorbed slowly from the gastrointestinal tract.
Theradione side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Theradione Patient Information
No information avaliable
Theradione Organisms Affected
Humans and other mammals
