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Theradione Brand names, Theradione Analogs

Theradione Brand Names Mixture

  • No information avaliable

Theradione Chemical_Formula


Theradione RX_link

No information avaliable

Theradione fda sheet

Theradione msds (material safety sheet)

Theradione MSDS

Theradione Synthesis Reference

No information avaliable

Theradione Molecular Weight

222.239 g/mol

Theradione Melting Point

148-151 oC

Theradione H2O Solubility

27 mg/L (at 20 oC)

Theradione State


Theradione LogP


Theradione Dosage Forms


Theradione Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Theradione Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Theradione Absorption

Absorbed slowly from the gastrointestinal tract.

Theradione side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Theradione Patient Information

No information avaliable

Theradione Organisms Affected

Humans and other mammals