Dineval
Dineval Brand names, Dineval Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Dineval Brand Names Mixture
- No information avaliable
Dineval Chemical_Formula
C15H10O2
Dineval RX_link
No information avaliable
Dineval fda sheet
Dineval msds (material safety sheet)
Dineval Synthesis Reference
No information avaliable
Dineval Molecular Weight
222.239 g/mol
Dineval Melting Point
148-151 oC
Dineval H2O Solubility
27 mg/L (at 20 oC)
Dineval State
Solid
Dineval LogP
2.917
Dineval Dosage Forms
Tablet
Dineval Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Dineval Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Dineval Absorption
Absorbed slowly from the gastrointestinal tract.
Dineval side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Dineval Patient Information
No information avaliable
Dineval Organisms Affected
Humans and other mammals
