Indema
Indema Brand names, Indema Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Indema Brand Names Mixture
- No information avaliable
Indema Chemical_Formula
C15H10O2
Indema RX_link
No information avaliable
Indema fda sheet
Indema msds (material safety sheet)
Indema Synthesis Reference
No information avaliable
Indema Molecular Weight
222.239 g/mol
Indema Melting Point
148-151 oC
Indema H2O Solubility
27 mg/L (at 20 oC)
Indema State
Solid
Indema LogP
2.917
Indema Dosage Forms
Tablet
Indema Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Indema Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Indema Absorption
Absorbed slowly from the gastrointestinal tract.
Indema side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Indema Patient Information
No information avaliable
Indema Organisms Affected
Humans and other mammals
