Trombol
Trombol Brand names, Trombol Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Trombol Brand Names Mixture
- No information avaliable
Trombol Chemical_Formula
C15H10O2
Trombol RX_link
No information avaliable
Trombol fda sheet
Trombol msds (material safety sheet)
Trombol Synthesis Reference
No information avaliable
Trombol Molecular Weight
222.239 g/mol
Trombol Melting Point
148-151 oC
Trombol H2O Solubility
27 mg/L (at 20 oC)
Trombol State
Solid
Trombol LogP
2.917
Trombol Dosage Forms
Tablet
Trombol Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Trombol Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Trombol Absorption
Absorbed slowly from the gastrointestinal tract.
Trombol side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Trombol Patient Information
No information avaliable
Trombol Organisms Affected
Humans and other mammals
