Eridione
Eridione Brand names, Eridione Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Eridione Brand Names Mixture
- No information avaliable
Eridione Chemical_Formula
C15H10O2
Eridione RX_link
No information avaliable
Eridione fda sheet
Eridione msds (material safety sheet)
Eridione Synthesis Reference
No information avaliable
Eridione Molecular Weight
222.239 g/mol
Eridione Melting Point
148-151 oC
Eridione H2O Solubility
27 mg/L (at 20 oC)
Eridione State
Solid
Eridione LogP
2.917
Eridione Dosage Forms
Tablet
Eridione Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Eridione Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Eridione Absorption
Absorbed slowly from the gastrointestinal tract.
Eridione side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Eridione Patient Information
No information avaliable
Eridione Organisms Affected
Humans and other mammals
