Eridione en es it fr

Eridione Brand names, Eridione Analogs

Eridione Brand Names Mixture

  • No information avaliable

Eridione Chemical_Formula

C15H10O2

Eridione RX_link

No information avaliable

Eridione fda sheet

Eridione msds (material safety sheet)

Eridione MSDS

Eridione Synthesis Reference

No information avaliable

Eridione Molecular Weight

222.239 g/mol

Eridione Melting Point

148-151 oC

Eridione H2O Solubility

27 mg/L (at 20 oC)

Eridione State

Solid

Eridione LogP

2.917

Eridione Dosage Forms

Tablet

Eridione Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Eridione Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Eridione Absorption

Absorbed slowly from the gastrointestinal tract.

Eridione side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Eridione Patient Information

No information avaliable

Eridione Organisms Affected

Humans and other mammals