Hemolidione
Hemolidione Brand names, Hemolidione Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Hemolidione Brand Names Mixture
- No information avaliable
Hemolidione Chemical_Formula
C15H10O2
Hemolidione RX_link
No information avaliable
Hemolidione fda sheet
Hemolidione msds (material safety sheet)
Hemolidione Synthesis Reference
No information avaliable
Hemolidione Molecular Weight
222.239 g/mol
Hemolidione Melting Point
148-151 oC
Hemolidione H2O Solubility
27 mg/L (at 20 oC)
Hemolidione State
Solid
Hemolidione LogP
2.917
Hemolidione Dosage Forms
Tablet
Hemolidione Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Hemolidione Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Hemolidione Absorption
Absorbed slowly from the gastrointestinal tract.
Hemolidione side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Hemolidione Patient Information
No information avaliable
Hemolidione Organisms Affected
Humans and other mammals
