Hemolidione en es it fr

Hemolidione Brand names, Hemolidione Analogs

Hemolidione Brand Names Mixture

  • No information avaliable

Hemolidione Chemical_Formula


Hemolidione RX_link

No information avaliable

Hemolidione fda sheet

Hemolidione msds (material safety sheet)

Hemolidione MSDS

Hemolidione Synthesis Reference

No information avaliable

Hemolidione Molecular Weight

222.239 g/mol

Hemolidione Melting Point

148-151 oC

Hemolidione H2O Solubility

27 mg/L (at 20 oC)

Hemolidione State


Hemolidione LogP


Hemolidione Dosage Forms


Hemolidione Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Hemolidione Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Hemolidione Absorption

Absorbed slowly from the gastrointestinal tract.

Hemolidione side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Hemolidione Patient Information

No information avaliable

Hemolidione Organisms Affected

Humans and other mammals