Phenyline
Phenyline Brand names, Phenyline Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Phenyline Brand Names Mixture
- No information avaliable
Phenyline Chemical_Formula
C15H10O2
Phenyline RX_link
No information avaliable
Phenyline fda sheet
Phenyline msds (material safety sheet)
Phenyline Synthesis Reference
No information avaliable
Phenyline Molecular Weight
222.239 g/mol
Phenyline Melting Point
148-151 oC
Phenyline H2O Solubility
27 mg/L (at 20 oC)
Phenyline State
Solid
Phenyline LogP
2.917
Phenyline Dosage Forms
Tablet
Phenyline Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Phenyline Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Phenyline Absorption
Absorbed slowly from the gastrointestinal tract.
Phenyline side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Phenyline Patient Information
No information avaliable
Phenyline Organisms Affected
Humans and other mammals
