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Phenyline Brand names, Phenyline Analogs

Phenyline Brand Names Mixture

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Phenyline Chemical_Formula


Phenyline RX_link

No information avaliable

Phenyline fda sheet

Phenyline msds (material safety sheet)

Phenyline MSDS

Phenyline Synthesis Reference

No information avaliable

Phenyline Molecular Weight

222.239 g/mol

Phenyline Melting Point

148-151 oC

Phenyline H2O Solubility

27 mg/L (at 20 oC)

Phenyline State


Phenyline LogP


Phenyline Dosage Forms


Phenyline Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Phenyline Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Phenyline Absorption

Absorbed slowly from the gastrointestinal tract.

Phenyline side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Phenyline Patient Information

No information avaliable

Phenyline Organisms Affected

Humans and other mammals