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Rectadione Brand names, Rectadione Analogs

Rectadione Brand Names Mixture

  • No information avaliable

Rectadione Chemical_Formula


Rectadione RX_link

No information avaliable

Rectadione fda sheet

Rectadione msds (material safety sheet)

Rectadione MSDS

Rectadione Synthesis Reference

No information avaliable

Rectadione Molecular Weight

222.239 g/mol

Rectadione Melting Point

148-151 oC

Rectadione H2O Solubility

27 mg/L (at 20 oC)

Rectadione State


Rectadione LogP


Rectadione Dosage Forms


Rectadione Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Rectadione Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Rectadione Absorption

Absorbed slowly from the gastrointestinal tract.

Rectadione side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Rectadione Patient Information

No information avaliable

Rectadione Organisms Affected

Humans and other mammals