Indion
Indion Brand names, Indion Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Indion Brand Names Mixture
- No information avaliable
Indion Chemical_Formula
C15H10O2
Indion RX_link
No information avaliable
Indion fda sheet
Indion msds (material safety sheet)
Indion Synthesis Reference
No information avaliable
Indion Molecular Weight
222.239 g/mol
Indion Melting Point
148-151 oC
Indion H2O Solubility
27 mg/L (at 20 oC)
Indion State
Solid
Indion LogP
2.917
Indion Dosage Forms
Tablet
Indion Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Indion Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Indion Absorption
Absorbed slowly from the gastrointestinal tract.
Indion side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Indion Patient Information
No information avaliable
Indion Organisms Affected
Humans and other mammals
