Phenhydren
Phenhydren Brand names, Phenhydren Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Phenhydren Brand Names Mixture
- No information avaliable
Phenhydren Chemical_Formula
C15H10O2
Phenhydren RX_link
No information avaliable
Phenhydren fda sheet
Phenhydren msds (material safety sheet)
Phenhydren Synthesis Reference
No information avaliable
Phenhydren Molecular Weight
222.239 g/mol
Phenhydren Melting Point
148-151 oC
Phenhydren H2O Solubility
27 mg/L (at 20 oC)
Phenhydren State
Solid
Phenhydren LogP
2.917
Phenhydren Dosage Forms
Tablet
Phenhydren Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Phenhydren Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Phenhydren Absorption
Absorbed slowly from the gastrointestinal tract.
Phenhydren side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Phenhydren Patient Information
No information avaliable
Phenhydren Organisms Affected
Humans and other mammals
