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Cronodione Brand names, Cronodione Analogs

Cronodione Brand Names Mixture

  • No information avaliable

Cronodione Chemical_Formula


Cronodione RX_link

No information avaliable

Cronodione fda sheet

Cronodione msds (material safety sheet)

Cronodione MSDS

Cronodione Synthesis Reference

No information avaliable

Cronodione Molecular Weight

222.239 g/mol

Cronodione Melting Point

148-151 oC

Cronodione H2O Solubility

27 mg/L (at 20 oC)

Cronodione State


Cronodione LogP


Cronodione Dosage Forms


Cronodione Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Cronodione Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Cronodione Absorption

Absorbed slowly from the gastrointestinal tract.

Cronodione side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Cronodione Patient Information

No information avaliable

Cronodione Organisms Affected

Humans and other mammals