Diadilan
Diadilan Brand names, Diadilan Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Diadilan Brand Names Mixture
- No information avaliable
Diadilan Chemical_Formula
C15H10O2
Diadilan RX_link
No information avaliable
Diadilan fda sheet
Diadilan msds (material safety sheet)
Diadilan Synthesis Reference
No information avaliable
Diadilan Molecular Weight
222.239 g/mol
Diadilan Melting Point
148-151 oC
Diadilan H2O Solubility
27 mg/L (at 20 oC)
Diadilan State
Solid
Diadilan LogP
2.917
Diadilan Dosage Forms
Tablet
Diadilan Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Diadilan Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Diadilan Absorption
Absorbed slowly from the gastrointestinal tract.
Diadilan side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Diadilan Patient Information
No information avaliable
Diadilan Organisms Affected
Humans and other mammals
