Danedion
Danedion Brand names, Danedion Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Danedion Brand Names Mixture
- No information avaliable
Danedion Chemical_Formula
C15H10O2
Danedion RX_link
No information avaliable
Danedion fda sheet
Danedion msds (material safety sheet)
Danedion Synthesis Reference
No information avaliable
Danedion Molecular Weight
222.239 g/mol
Danedion Melting Point
148-151 oC
Danedion H2O Solubility
27 mg/L (at 20 oC)
Danedion State
Solid
Danedion LogP
2.917
Danedion Dosage Forms
Tablet
Danedion Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Danedion Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Danedion Absorption
Absorbed slowly from the gastrointestinal tract.
Danedion side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Danedion Patient Information
No information avaliable
Danedion Organisms Affected
Humans and other mammals
