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Pindione Brand names, Pindione Analogs

Pindione Brand Names Mixture

  • No information avaliable

Pindione Chemical_Formula


Pindione RX_link

No information avaliable

Pindione fda sheet

Pindione msds (material safety sheet)

Pindione MSDS

Pindione Synthesis Reference

No information avaliable

Pindione Molecular Weight

222.239 g/mol

Pindione Melting Point

148-151 oC

Pindione H2O Solubility

27 mg/L (at 20 oC)

Pindione State


Pindione LogP


Pindione Dosage Forms


Pindione Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Pindione Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Pindione Absorption

Absorbed slowly from the gastrointestinal tract.

Pindione side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Pindione Patient Information

No information avaliable

Pindione Organisms Affected

Humans and other mammals