Dindevan
Dindevan Brand names, Dindevan Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Dindevan Brand Names Mixture
- No information avaliable
Dindevan Chemical_Formula
C15H10O2
Dindevan RX_link
No information avaliable
Dindevan fda sheet
Dindevan msds (material safety sheet)
Dindevan Synthesis Reference
No information avaliable
Dindevan Molecular Weight
222.239 g/mol
Dindevan Melting Point
148-151 oC
Dindevan H2O Solubility
27 mg/L (at 20 oC)
Dindevan State
Solid
Dindevan LogP
2.917
Dindevan Dosage Forms
Tablet
Dindevan Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Dindevan Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Dindevan Absorption
Absorbed slowly from the gastrointestinal tract.
Dindevan side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Dindevan Patient Information
No information avaliable
Dindevan Organisms Affected
Humans and other mammals
