Danilone
Danilone Brand names, Danilone Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Danilone Brand Names Mixture
- No information avaliable
Danilone Chemical_Formula
C15H10O2
Danilone RX_link
No information avaliable
Danilone fda sheet
Danilone msds (material safety sheet)
Danilone Synthesis Reference
No information avaliable
Danilone Molecular Weight
222.239 g/mol
Danilone Melting Point
148-151 oC
Danilone H2O Solubility
27 mg/L (at 20 oC)
Danilone State
Solid
Danilone LogP
2.917
Danilone Dosage Forms
Tablet
Danilone Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Danilone Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Danilone Absorption
Absorbed slowly from the gastrointestinal tract.
Danilone side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Danilone Patient Information
No information avaliable
Danilone Organisms Affected
Humans and other mammals
