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Emandione Brand names, Emandione Analogs

Emandione Brand Names Mixture

  • No information avaliable

Emandione Chemical_Formula


Emandione RX_link

No information avaliable

Emandione fda sheet

Emandione msds (material safety sheet)

Emandione MSDS

Emandione Synthesis Reference

No information avaliable

Emandione Molecular Weight

222.239 g/mol

Emandione Melting Point

148-151 oC

Emandione H2O Solubility

27 mg/L (at 20 oC)

Emandione State


Emandione LogP


Emandione Dosage Forms


Emandione Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Emandione Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Emandione Absorption

Absorbed slowly from the gastrointestinal tract.

Emandione side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Emandione Patient Information

No information avaliable

Emandione Organisms Affected

Humans and other mammals