Athrombon
Athrombon Brand names, Athrombon Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Athrombon Brand Names Mixture
- No information avaliable
Athrombon Chemical_Formula
C15H10O2
Athrombon RX_link
No information avaliable
Athrombon fda sheet
Athrombon msds (material safety sheet)
Athrombon Synthesis Reference
No information avaliable
Athrombon Molecular Weight
222.239 g/mol
Athrombon Melting Point
148-151 oC
Athrombon H2O Solubility
27 mg/L (at 20 oC)
Athrombon State
Solid
Athrombon LogP
2.917
Athrombon Dosage Forms
Tablet
Athrombon Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Athrombon Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Athrombon Absorption
Absorbed slowly from the gastrointestinal tract.
Athrombon side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Athrombon Patient Information
No information avaliable
Athrombon Organisms Affected
Humans and other mammals
