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Athrombon Brand names, Athrombon Analogs

Athrombon Brand Names Mixture

  • No information avaliable

Athrombon Chemical_Formula

C15H10O2

Athrombon RX_link

No information avaliable

Athrombon fda sheet

Athrombon msds (material safety sheet)

Athrombon MSDS

Athrombon Synthesis Reference

No information avaliable

Athrombon Molecular Weight

222.239 g/mol

Athrombon Melting Point

148-151 oC

Athrombon H2O Solubility

27 mg/L (at 20 oC)

Athrombon State

Solid

Athrombon LogP

2.917

Athrombon Dosage Forms

Tablet

Athrombon Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Athrombon Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Athrombon Absorption

Absorbed slowly from the gastrointestinal tract.

Athrombon side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Athrombon Patient Information

No information avaliable

Athrombon Organisms Affected

Humans and other mammals