Emandion
Emandion Brand names, Emandion Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Emandion Brand Names Mixture
- No information avaliable
Emandion Chemical_Formula
C15H10O2
Emandion RX_link
No information avaliable
Emandion fda sheet
Emandion msds (material safety sheet)
Emandion Synthesis Reference
No information avaliable
Emandion Molecular Weight
222.239 g/mol
Emandion Melting Point
148-151 oC
Emandion H2O Solubility
27 mg/L (at 20 oC)
Emandion State
Solid
Emandion LogP
2.917
Emandion Dosage Forms
Tablet
Emandion Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Emandion Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Emandion Absorption
Absorbed slowly from the gastrointestinal tract.
Emandion side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Emandion Patient Information
No information avaliable
Emandion Organisms Affected
Humans and other mammals
