Indon
Indon Brand names, Indon Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Indon Brand Names Mixture
- No information avaliable
Indon Chemical_Formula
C15H10O2
Indon RX_link
No information avaliable
Indon fda sheet
Indon msds (material safety sheet)
Indon Synthesis Reference
No information avaliable
Indon Molecular Weight
222.239 g/mol
Indon Melting Point
148-151 oC
Indon H2O Solubility
27 mg/L (at 20 oC)
Indon State
Solid
Indon LogP
2.917
Indon Dosage Forms
Tablet
Indon Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Indon Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Indon Absorption
Absorbed slowly from the gastrointestinal tract.
Indon side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Indon Patient Information
No information avaliable
Indon Organisms Affected
Humans and other mammals
