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Indon Brand names, Indon Analogs

Indon Brand Names Mixture

  • No information avaliable

Indon Chemical_Formula

C15H10O2

Indon RX_link

No information avaliable

Indon fda sheet

Indon msds (material safety sheet)

Indon MSDS

Indon Synthesis Reference

No information avaliable

Indon Molecular Weight

222.239 g/mol

Indon Melting Point

148-151 oC

Indon H2O Solubility

27 mg/L (at 20 oC)

Indon State

Solid

Indon LogP

2.917

Indon Dosage Forms

Tablet

Indon Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Indon Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Indon Absorption

Absorbed slowly from the gastrointestinal tract.

Indon side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Indon Patient Information

No information avaliable

Indon Organisms Affected

Humans and other mammals