Phenyllin
Phenyllin Brand names, Phenyllin Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Phenyllin Brand Names Mixture
- No information avaliable
Phenyllin Chemical_Formula
C15H10O2
Phenyllin RX_link
No information avaliable
Phenyllin fda sheet
Phenyllin msds (material safety sheet)
Phenyllin Synthesis Reference
No information avaliable
Phenyllin Molecular Weight
222.239 g/mol
Phenyllin Melting Point
148-151 oC
Phenyllin H2O Solubility
27 mg/L (at 20 oC)
Phenyllin State
Solid
Phenyllin LogP
2.917
Phenyllin Dosage Forms
Tablet
Phenyllin Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Phenyllin Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Phenyllin Absorption
Absorbed slowly from the gastrointestinal tract.
Phenyllin side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Phenyllin Patient Information
No information avaliable
Phenyllin Organisms Affected
Humans and other mammals
