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Diophindane Brand names, Diophindane Analogs

Diophindane Brand Names Mixture

  • No information avaliable

Diophindane Chemical_Formula


Diophindane RX_link

No information avaliable

Diophindane fda sheet

Diophindane msds (material safety sheet)

Diophindane MSDS

Diophindane Synthesis Reference

No information avaliable

Diophindane Molecular Weight

222.239 g/mol

Diophindane Melting Point

148-151 oC

Diophindane H2O Solubility

27 mg/L (at 20 oC)

Diophindane State


Diophindane LogP


Diophindane Dosage Forms


Diophindane Indication

For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.

Diophindane Pharmacology

Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.

Diophindane Absorption

Absorbed slowly from the gastrointestinal tract.

Diophindane side effects and Toxicity

Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.

Diophindane Patient Information

No information avaliable

Diophindane Organisms Affected

Humans and other mammals