Phenylin
Phenylin Brand names, Phenylin Analogs
- Athrombon
- Bindan
- Cronodione
- Danedion
- Danilon
- Danilone
- Diadilan
- Dindevan
- Dineval
- Diophindane
- Emandion
- Emandione
- Eridione
- Fenhydren
- Fenilin
- Fenindion
- Hedulin
- Hemolidione
- Indema
- Indion
- Indon
- PID
- Phenhydren
- Phenillin
- Phenylen
- Phenylin
- Phenylindanedione
- Phenylindione
- Phenyline
- Phenyllin
- Pindione
- Rectadione
- Theradione
- Thrombasal
- Tromazal
- Trombol
Phenylin Brand Names Mixture
- No information avaliable
Phenylin Chemical_Formula
C15H10O2
Phenylin RX_link
No information avaliable
Phenylin fda sheet
Phenylin msds (material safety sheet)
Phenylin Synthesis Reference
No information avaliable
Phenylin Molecular Weight
222.239 g/mol
Phenylin Melting Point
148-151 oC
Phenylin H2O Solubility
27 mg/L (at 20 oC)
Phenylin State
Solid
Phenylin LogP
2.917
Phenylin Dosage Forms
Tablet
Phenylin Indication
For the treatment of pulmonary embolism, cardiomyopathy, atrial fibrillation and flutter, cerebral embolism, mural thrombosis, and thrombophili. Also used for anticoagulant prophylaxis.
Phenylin Pharmacology
Phenindione thins the blood by antagonizing vitamin K which is required for the production of clotting factors in the liver. Anticoagulants such as Phenindione have no direct effect on an established thrombus, nor do they reverse ischemic tissue damage (damage caused by an inadequate blood supply to an organ or part of the body). However, once a thrombus has occurred, the goal of anticoagulant treatment is to prevent further extension of the formed clot and prevent secondary thromboembolic complications which may result in serious and possibly fatal sequelae. Phenindione has actions similar to warfarin, but it is now rarely employed because of its higer incidence of severe adverse effects.
Phenylin Absorption
Absorbed slowly from the gastrointestinal tract.
Phenylin side effects and Toxicity
Oral, mouse: LD50 = 175 mg/kg; Oral, rat: LD50 = 163 mg/kg.
Phenylin Patient Information
No information avaliable
Phenylin Organisms Affected
Humans and other mammals
