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Imipramine Brand names, Imipramine Analogs

Imipramine Brand Names Mixture

  • No information avaliable

Imipramine Chemical_Formula


Imipramine RX_link

Imipramine fda sheet

Imipramine FDA

Imipramine msds (material safety sheet)

Imipramine Synthesis Reference

No information avaliable

Imipramine Molecular Weight

280.407 g/mol

Imipramine Melting Point

174.5 oC

Imipramine H2O Solubility

18.2 mg/L

Imipramine State


Imipramine LogP


Imipramine Dosage Forms


Imipramine Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Imipramine Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Imipramine Absorption

Rapidly and well absorbed after oral administration

Imipramine side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Imipramine Patient Information

Imipramine Organisms Affected

Humans and other mammals