Tofraniln A en es it fr

Tofraniln A Brand names, Tofraniln A Analogs

Tofraniln A Brand Names Mixture

  • No information avaliable

Tofraniln A Chemical_Formula

C19H24N2

Tofraniln A RX_link

http://www.rxlist.com/cgi/generic/imip.htm

Tofraniln A fda sheet

Tofraniln_A FDA

Tofraniln A msds (material safety sheet)

Tofraniln A Synthesis Reference

No information avaliable

Tofraniln A Molecular Weight

280.407 g/mol

Tofraniln A Melting Point

174.5 oC

Tofraniln A H2O Solubility

18.2 mg/L

Tofraniln A State

Solid

Tofraniln A LogP

4.184

Tofraniln A Dosage Forms

Tablet

Tofraniln A Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Tofraniln A Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Tofraniln A Absorption

Rapidly and well absorbed after oral administration

Tofraniln A side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Tofraniln A Patient Information

Tofraniln A Organisms Affected

Humans and other mammals