Imavate
Brand names,
Imavate
Analogs
Imavate
Brand Names Mixture
Imavate
Chemical_Formula
C19H24N2
Imavate
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Imavate
fda sheet
Imavate
msds (material safety sheet)
Imavate
Synthesis Reference
No information avaliable
Imavate
Molecular Weight
280.407 g/mol
Imavate
Melting Point
174.5 oC
Imavate
H2O Solubility
18.2 mg/L
Imavate
State
Solid
Imavate
LogP
4.184
Imavate
Dosage Forms
Tablet
Imavate
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Imavate
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Imavate
Absorption
Rapidly and well absorbed after oral administration
Imavate
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Imavate
Patient Information
Imavate
Organisms Affected
Humans and other mammals