Surplix en es it fr

Surplix Brand names, Surplix Analogs

Surplix Brand Names Mixture

  • No information avaliable

Surplix Chemical_Formula


Surplix RX_link

Surplix fda sheet

Surplix FDA

Surplix msds (material safety sheet)

Surplix Synthesis Reference

No information avaliable

Surplix Molecular Weight

280.407 g/mol

Surplix Melting Point

174.5 oC

Surplix H2O Solubility

18.2 mg/L

Surplix State


Surplix LogP


Surplix Dosage Forms


Surplix Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Surplix Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Surplix Absorption

Rapidly and well absorbed after oral administration

Surplix side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Surplix Patient Information

Surplix Organisms Affected

Humans and other mammals