Melipramin
Brand names,
Melipramin
Analogs
Melipramin
Brand Names Mixture
Melipramin
Chemical_Formula
C19H24N2
Melipramin
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Melipramin
fda sheet
Melipramin
msds (material safety sheet)
Melipramin
Synthesis Reference
No information avaliable
Melipramin
Molecular Weight
280.407 g/mol
Melipramin
Melting Point
174.5 oC
Melipramin
H2O Solubility
18.2 mg/L
Melipramin
State
Solid
Melipramin
LogP
4.184
Melipramin
Dosage Forms
Tablet
Melipramin
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Melipramin
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Melipramin
Absorption
Rapidly and well absorbed after oral administration
Melipramin
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Melipramin
Patient Information
Melipramin
Organisms Affected
Humans and other mammals