Trimipramine Maleate
Brand names,
Trimipramine Maleate
Analogs
Trimipramine Maleate
Brand Names Mixture
Trimipramine Maleate
Chemical_Formula
C19H24N2
Trimipramine Maleate
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Trimipramine Maleate
fda sheet
Trimipramine Maleate
msds (material safety sheet)
Trimipramine Maleate
Synthesis Reference
No information avaliable
Trimipramine Maleate
Molecular Weight
280.407 g/mol
Trimipramine Maleate
Melting Point
174.5 oC
Trimipramine Maleate
H2O Solubility
18.2 mg/L
Trimipramine Maleate
State
Solid
Trimipramine Maleate
LogP
4.184
Trimipramine Maleate
Dosage Forms
Tablet
Trimipramine Maleate
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Trimipramine Maleate
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Trimipramine Maleate
Absorption
Rapidly and well absorbed after oral administration
Trimipramine Maleate
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Trimipramine Maleate
Patient Information
Trimipramine Maleate
Organisms Affected
Humans and other mammals