Irmin
Brand names,
Irmin
Analogs
Irmin
Brand Names Mixture
Irmin
Chemical_Formula
C19H24N2
Irmin
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Irmin
fda sheet
Irmin
msds (material safety sheet)
Irmin
Synthesis Reference
No information avaliable
Irmin
Molecular Weight
280.407 g/mol
Irmin
Melting Point
174.5 oC
Irmin
H2O Solubility
18.2 mg/L
Irmin
State
Solid
Irmin
LogP
4.184
Irmin
Dosage Forms
Tablet
Irmin
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Irmin
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Irmin
Absorption
Rapidly and well absorbed after oral administration
Irmin
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Irmin
Patient Information
Irmin
Organisms Affected
Humans and other mammals