Imizine
Brand names,
Imizine
Analogs
Imizine
Brand Names Mixture
Imizine
Chemical_Formula
C19H24N2
Imizine
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Imizine
fda sheet
Imizine
msds (material safety sheet)
Imizine
Synthesis Reference
No information avaliable
Imizine
Molecular Weight
280.407 g/mol
Imizine
Melting Point
174.5 oC
Imizine
H2O Solubility
18.2 mg/L
Imizine
State
Solid
Imizine
LogP
4.184
Imizine
Dosage Forms
Tablet
Imizine
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Imizine
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Imizine
Absorption
Rapidly and well absorbed after oral administration
Imizine
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Imizine
Patient Information
Imizine
Organisms Affected
Humans and other mammals