Tipramine
Brand names,
Tipramine
Analogs
Tipramine
Brand Names Mixture
Tipramine
Chemical_Formula
C19H24N2
Tipramine
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Tipramine
fda sheet
Tipramine
msds (material safety sheet)
Tipramine
Synthesis Reference
No information avaliable
Tipramine
Molecular Weight
280.407 g/mol
Tipramine
Melting Point
174.5 oC
Tipramine
H2O Solubility
18.2 mg/L
Tipramine
State
Solid
Tipramine
LogP
4.184
Tipramine
Dosage Forms
Tablet
Tipramine
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Tipramine
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Tipramine
Absorption
Rapidly and well absorbed after oral administration
Tipramine
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Tipramine
Patient Information
Tipramine
Organisms Affected
Humans and other mammals