Tofranil-Pm en es it fr

Tofranil-Pm Brand names, Tofranil-Pm Analogs

Tofranil-Pm Brand Names Mixture

  • No information avaliable

Tofranil-Pm Chemical_Formula


Tofranil-Pm RX_link

Tofranil-Pm fda sheet

Tofranil-Pm FDA

Tofranil-Pm msds (material safety sheet)

Tofranil-Pm Synthesis Reference

No information avaliable

Tofranil-Pm Molecular Weight

280.407 g/mol

Tofranil-Pm Melting Point

174.5 oC

Tofranil-Pm H2O Solubility

18.2 mg/L

Tofranil-Pm State


Tofranil-Pm LogP


Tofranil-Pm Dosage Forms


Tofranil-Pm Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Tofranil-Pm Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Tofranil-Pm Absorption

Rapidly and well absorbed after oral administration

Tofranil-Pm side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Tofranil-Pm Patient Information

Tofranil-Pm Organisms Affected

Humans and other mammals