Dynaprin
Brand names,
Dynaprin
Analogs
Dynaprin
Brand Names Mixture
Dynaprin
Chemical_Formula
C19H24N2
Dynaprin
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Dynaprin
fda sheet
Dynaprin
msds (material safety sheet)
Dynaprin
Synthesis Reference
No information avaliable
Dynaprin
Molecular Weight
280.407 g/mol
Dynaprin
Melting Point
174.5 oC
Dynaprin
H2O Solubility
18.2 mg/L
Dynaprin
State
Solid
Dynaprin
LogP
4.184
Dynaprin
Dosage Forms
Tablet
Dynaprin
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Dynaprin
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Dynaprin
Absorption
Rapidly and well absorbed after oral administration
Dynaprin
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Dynaprin
Patient Information
Dynaprin
Organisms Affected
Humans and other mammals