Imizin
Brand names,
Imizin
Analogs
Imizin
Brand Names Mixture
Imizin
Chemical_Formula
C19H24N2
Imizin
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Imizin
fda sheet
Imizin
msds (material safety sheet)
Imizin
Synthesis Reference
No information avaliable
Imizin
Molecular Weight
280.407 g/mol
Imizin
Melting Point
174.5 oC
Imizin
H2O Solubility
18.2 mg/L
Imizin
State
Solid
Imizin
LogP
4.184
Imizin
Dosage Forms
Tablet
Imizin
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Imizin
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Imizin
Absorption
Rapidly and well absorbed after oral administration
Imizin
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Imizin
Patient Information
Imizin
Organisms Affected
Humans and other mammals