Janimine

Janimine Brand names, Janimine Analogs

Janimine Brand Names Mixture

No information avaliable

Janimine Chemical_Formula

C₁₉H₂₄N₂

Janimine RX_link

http://www.rxlist.com/cgi/generic/imip.htm

Janimine fda sheet

Janimine FDA

Janimine msds (material safety sheet)

Janimine Synthesis Reference

No information avaliable

Janimine Molecular Weight

280.407 g/mol

Janimine Melting Point

174.5 ^oC

Janimine H₂O Solubility

18.2 mg/L

Janimine State

Solid

Janimine LogP

4.184

Janimine Dosage Forms

Tablet

Janimine Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Janimine Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Janimine Absorption

Rapidly and well absorbed after oral administration

Janimine side effects and Toxicity

Oral, rat LD₅₀: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Janimine Patient Information

Janimine Organisms Affected

Humans and other mammals