Sk-Pramine en es it fr

Sk-Pramine Brand names, Sk-Pramine Analogs

Sk-Pramine Brand Names Mixture

  • No information avaliable

Sk-Pramine Chemical_Formula


Sk-Pramine RX_link

Sk-Pramine fda sheet

Sk-Pramine FDA

Sk-Pramine msds (material safety sheet)

Sk-Pramine Synthesis Reference

No information avaliable

Sk-Pramine Molecular Weight

280.407 g/mol

Sk-Pramine Melting Point

174.5 oC

Sk-Pramine H2O Solubility

18.2 mg/L

Sk-Pramine State


Sk-Pramine LogP


Sk-Pramine Dosage Forms


Sk-Pramine Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Sk-Pramine Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Sk-Pramine Absorption

Rapidly and well absorbed after oral administration

Sk-Pramine side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Sk-Pramine Patient Information

Sk-Pramine Organisms Affected

Humans and other mammals