Nelipramin
Brand names,
Nelipramin
Analogs
Nelipramin
Brand Names Mixture
Nelipramin
Chemical_Formula
C19H24N2
Nelipramin
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Nelipramin
fda sheet
Nelipramin
msds (material safety sheet)
Nelipramin
Synthesis Reference
No information avaliable
Nelipramin
Molecular Weight
280.407 g/mol
Nelipramin
Melting Point
174.5 oC
Nelipramin
H2O Solubility
18.2 mg/L
Nelipramin
State
Solid
Nelipramin
LogP
4.184
Nelipramin
Dosage Forms
Tablet
Nelipramin
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Nelipramin
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Nelipramin
Absorption
Rapidly and well absorbed after oral administration
Nelipramin
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Nelipramin
Patient Information
Nelipramin
Organisms Affected
Humans and other mammals