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DPID Brand names, DPID Analogs

DPID Brand Names Mixture

  • No information avaliable

DPID Chemical_Formula

C19H24N2

DPID RX_link

http://www.rxlist.com/cgi/generic/imip.htm

DPID fda sheet

DPID FDA

DPID msds (material safety sheet)

DPID Synthesis Reference

No information avaliable

DPID Molecular Weight

280.407 g/mol

DPID Melting Point

174.5 oC

DPID H2O Solubility

18.2 mg/L

DPID State

Solid

DPID LogP

4.184

DPID Dosage Forms

Tablet

DPID Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

DPID Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

DPID Absorption

Rapidly and well absorbed after oral administration

DPID side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

DPID Patient Information

DPID Organisms Affected

Humans and other mammals