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Berkomine Brand names, Berkomine Analogs

Berkomine Brand Names Mixture

  • No information avaliable

Berkomine Chemical_Formula

C19H24N2

Berkomine RX_link

http://www.rxlist.com/cgi/generic/imip.htm

Berkomine fda sheet

Berkomine FDA

Berkomine msds (material safety sheet)

Berkomine Synthesis Reference

No information avaliable

Berkomine Molecular Weight

280.407 g/mol

Berkomine Melting Point

174.5 oC

Berkomine H2O Solubility

18.2 mg/L

Berkomine State

Solid

Berkomine LogP

4.184

Berkomine Dosage Forms

Tablet

Berkomine Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Berkomine Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Berkomine Absorption

Rapidly and well absorbed after oral administration

Berkomine side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Berkomine Patient Information

Berkomine Organisms Affected

Humans and other mammals