Intalpram
Brand names,
Intalpram
Analogs
Intalpram
Brand Names Mixture
Intalpram
Chemical_Formula
C19H24N2
Intalpram
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Intalpram
fda sheet
Intalpram
msds (material safety sheet)
Intalpram
Synthesis Reference
No information avaliable
Intalpram
Molecular Weight
280.407 g/mol
Intalpram
Melting Point
174.5 oC
Intalpram
H2O Solubility
18.2 mg/L
Intalpram
State
Solid
Intalpram
LogP
4.184
Intalpram
Dosage Forms
Tablet
Intalpram
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Intalpram
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Intalpram
Absorption
Rapidly and well absorbed after oral administration
Intalpram
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Intalpram
Patient Information
Intalpram
Organisms Affected
Humans and other mammals