Pramine
Pramine Brand names, Pramine Analogs
- Antideprin
- Apo-Imipramine
- Berkomine
- Censtim
- Censtin
- DPID
- Declomipramine
- Dimipressin
- Dyna-Zina
- Dynaprin
- Estraldine
- Eupramin
- IM
- Imavate
- Imidobenzyle
- Imipramina
- Imipramine Hcl
- Imiprin
- Imizin
- Imizine
- Imizinum
- Impramine
- Impril
- Intalpram
- Iramil
- Irmin
- Janimine
- Melipramin
- Melipramine
- Nelipramin
- Norfranil
- Novopramine
- Pramine
- Prazepine
- Presamine
- Promiben
- Psychoforin
- Sk-Pramine
- Surmontil
- Surplix
- Timolet
- Tipramine
- Tofranil
- Tofranil, Base
- Tofranil-Pm
- Tofraniln A
- Trimipramine Maleate
Pramine Brand Names Mixture
- No information avaliable
Pramine Chemical_Formula
C19H24N2
Pramine RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Pramine fda sheet
Pramine msds (material safety sheet)
Pramine Synthesis Reference
No information avaliable
Pramine Molecular Weight
280.407 g/mol
Pramine Melting Point
174.5 oC
Pramine H2O Solubility
18.2 mg/L
Pramine State
Solid
Pramine LogP
4.184
Pramine Dosage Forms
Tablet
Pramine Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Pramine Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Pramine Absorption
Rapidly and well absorbed after oral administration
Pramine side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Pramine Patient Information
Pramine Organisms Affected
Humans and other mammals
