Norfranil en es it fr

Norfranil Brand names, Norfranil Analogs

Norfranil Brand Names Mixture

  • No information avaliable

Norfranil Chemical_Formula

C19H24N2

Norfranil RX_link

http://www.rxlist.com/cgi/generic/imip.htm

Norfranil fda sheet

Norfranil FDA

Norfranil msds (material safety sheet)

Norfranil Synthesis Reference

No information avaliable

Norfranil Molecular Weight

280.407 g/mol

Norfranil Melting Point

174.5 oC

Norfranil H2O Solubility

18.2 mg/L

Norfranil State

Solid

Norfranil LogP

4.184

Norfranil Dosage Forms

Tablet

Norfranil Indication

For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.

Norfranil Pharmacology

Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.

Norfranil Absorption

Rapidly and well absorbed after oral administration

Norfranil side effects and Toxicity

Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.

Norfranil Patient Information

Norfranil Organisms Affected

Humans and other mammals