Imiprin
Brand names,
Imiprin
Analogs
Imiprin
Brand Names Mixture
Imiprin
Chemical_Formula
C19H24N2
Imiprin
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Imiprin
fda sheet
Imiprin
msds (material safety sheet)
Imiprin
Synthesis Reference
No information avaliable
Imiprin
Molecular Weight
280.407 g/mol
Imiprin
Melting Point
174.5 oC
Imiprin
H2O Solubility
18.2 mg/L
Imiprin
State
Solid
Imiprin
LogP
4.184
Imiprin
Dosage Forms
Tablet
Imiprin
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Imiprin
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Imiprin
Absorption
Rapidly and well absorbed after oral administration
Imiprin
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Imiprin
Patient Information
Imiprin
Organisms Affected
Humans and other mammals