Dimipressin
Brand names,
Dimipressin
Analogs
Dimipressin
Brand Names Mixture
Dimipressin
Chemical_Formula
C19H24N2
Dimipressin
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Dimipressin
fda sheet
Dimipressin
msds (material safety sheet)
Dimipressin
Synthesis Reference
No information avaliable
Dimipressin
Molecular Weight
280.407 g/mol
Dimipressin
Melting Point
174.5 oC
Dimipressin
H2O Solubility
18.2 mg/L
Dimipressin
State
Solid
Dimipressin
LogP
4.184
Dimipressin
Dosage Forms
Tablet
Dimipressin
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Dimipressin
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Dimipressin
Absorption
Rapidly and well absorbed after oral administration
Dimipressin
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Dimipressin
Patient Information
Dimipressin
Organisms Affected
Humans and other mammals