Prazepine
Brand names,
Prazepine
Analogs
Prazepine
Brand Names Mixture
Prazepine
Chemical_Formula
C19H24N2
Prazepine
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Prazepine
fda sheet
Prazepine
msds (material safety sheet)
Prazepine
Synthesis Reference
No information avaliable
Prazepine
Molecular Weight
280.407 g/mol
Prazepine
Melting Point
174.5 oC
Prazepine
H2O Solubility
18.2 mg/L
Prazepine
State
Solid
Prazepine
LogP
4.184
Prazepine
Dosage Forms
Tablet
Prazepine
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Prazepine
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Prazepine
Absorption
Rapidly and well absorbed after oral administration
Prazepine
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Prazepine
Patient Information
Prazepine
Organisms Affected
Humans and other mammals