Dyna-Zina
Brand names,
Dyna-Zina
Analogs
Dyna-Zina
Brand Names Mixture
Dyna-Zina
Chemical_Formula
C19H24N2
Dyna-Zina
RX_link
http://www.rxlist.com/cgi/generic/imip.htm
Dyna-Zina
fda sheet
Dyna-Zina
msds (material safety sheet)
Dyna-Zina
Synthesis Reference
No information avaliable
Dyna-Zina
Molecular Weight
280.407 g/mol
Dyna-Zina
Melting Point
174.5 oC
Dyna-Zina
H2O Solubility
18.2 mg/L
Dyna-Zina
State
Solid
Dyna-Zina
LogP
4.184
Dyna-Zina
Dosage Forms
Tablet
Dyna-Zina
Indication
For the relief of symptoms of depression and as temporary adjunctive therapy in reducing enuresis in children aged 6 years and older.
Dyna-Zina
Pharmacology
Imipramine is a tricyclic antidepressant with general pharmacological properties similar to those of structurally related tricyclic antidepressant drugs such as amitriptyline and doxepin. A tertiary amine, imipramine inhibits the reuptake of serotonin more so than most secondary amine tricyclics, meaning that it blocks the reuptake of neurotransmitters serotonin and noradrenaline almost equally. It is also effective in migraine prophylaxis, but not in abortion of acute migraine attack.
Dyna-Zina
Absorption
Rapidly and well absorbed after oral administration
Dyna-Zina
side effects and Toxicity
Oral, rat LD50: 355 to 682 mg/kg. Toxic signs proceed progressively from depression, irregular respiration and ataxia to convulsions and death.
Dyna-Zina
Patient Information
Dyna-Zina
Organisms Affected
Humans and other mammals